Idle gossip about validity of intralesional steroid injection in treating central giant cell granuloma

Intralesional corticosteroid injection for central giant cell granuloma. A case report.

Central giant cell granuloma (CGCG) is a benign intraosseous lesion of the jaws that is found predominantly in children and young adults. Although benign, it may be locally aggressive, causing extensive bone destruction, tooth displacement and root resorption. The common therapy is aggressive curettage, peripheral ostectomy or resection, which may be associated with loss of teeth and, in younge...

Multifocal Central Giant Cell Granuloma - A Case Report

Central giant cell granuloma is a benign, aggressive neoplasm composed of multinucleated giant cells that almost exclusively occurs in the jaws though extra-gnathic incidence is rare.Multifocal CGCGs of the jaws are very rare and suggestive of systemic diseases such as hyperparathyroidism,an inherited syndrome such as Noonan-like multiple giant cell lesion syndrome or other disorders.Very few c...

Fine needle aspiration cytology and intralesional steroid injection in a central giant cell granuloma affecting the gingiva: a new clinical approach.

Central giant cell granuloma (CGCG) is a benign jaw lesion predominantly found in the mandible of young female patients with a variable clinical behavior. Although surgical management is regarded as the main treatment modality for this lesion, the use of intralesional injections of steroids has been recently advocated for its treatment. In addition to this conservative management, the use of fi...

Commentary on: Injection of Steroids Intralesional in Central Giant Cell Granuloma Cases (Giant Cell Tumor): Is it Free of Systemic Complications or Not?

A Comparative Immunohistochemical Study of CD105 Expression in Peripheral and Central Giant Cell Granuloma

Introduction: Despite similar histopathological features, peripheral giant cell granuloma (PGCG) and central giant cell granuloma (CGCG) differ in their biological behavior. PGCG and CGCG are hemorrhagic/vascular lesions, clinically and microscopically. Angiogenesis is necessary for the growth and development of lesions and affects their clinical behavior. CD105 is a useful vascular marker for...